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Supercomputer simulations have mapped the full motions of the spliceosome inside a two-million-atom model of the human cell.
Top 12 Science & Health Discoveries
- Supercomputer maps spliceosome motions • 29 March 2026
- Polarity inversion origin revealed in polymer semiconductors • 29 March 2026
- Ancient DNA shows earliest dogs lived with Ice Age humans • 29 March 2026
- Magnetic waves detected deep inside the Sun • 29 March 2026
- Human brain operates near, not at, critical point • 29 March 2026
- New enzyme atlas rewrites E3 ligase biology • 29 March 2026
- Emissions cuts can mask lack of system-wide climate progress • 29 March 2026
- North Sea wind farms altering sediment flows • 29 March 2026
- AI framework discovers new carbon structures • 29 March 2026
- Electricity drives biomass-based chemical production • 29 March 2026
- Solar cells exceed 100% efficiency via singlet fission • 29 March 2026
- New carbon material improves carbon capture • 29 March 2026
Researchers at the Italian Institute of Technology, in collaboration with Uppsala University and AstraZeneca, used computational chemistry and supercomputers to simulate the movements of the spliceosome within a two-million-atom human cell model.
The work reveals fundamental mechanisms of gene expression and offers a new way to understand cellular processes that were previously inaccessible.
Source: phys.org
A team led by Prof. Boseok Kang at Sungkyunkwan University identified why polarity inversion occurs in only certain polymer semiconductors.
The discovery, published in Advanced Functional Materials, clarifies a long-standing puzzle and could improve design of next-generation flexible electronics.
Source: phys.org
Analysis of ancient DNA indicates dogs were widely distributed across Western Eurasia during the Palaeolithic and lived alongside humans much earlier than previously thought.
The study published in Nature pushes back the timeline of one of humanity’s oldest partnerships.
Source: phys.org
Researchers at NYU Abu Dhabi discovered large-scale magnetic waves moving deep within the Sun, driven by fields far below the surface.
These waves provide a new window into the Sun’s inaccessible interior and may improve predictions of solar activity.
Source: phys.org
A study in Physical Review Letters shows that many signatures of criticality in brain data are statistical artifacts and confirms the brain functions near but not exactly at a critical point.
The more robust framework applied to whole-brain fMRI data refines our understanding of how the brain balances order and flexibility.
Source: phys.org
WEHI researchers led a global effort to create the first authoritative atlas of all human E3 ligases, resolving nearly two decades of inconsistencies.
Published in Cell, the gold-standard reference covers enzymes that regulate almost every cellular process and should accelerate research across biology and medicine.
Source: phys.org
A team led by Germán Bersalli analyzed four European countries and found that focusing only on emissions reductions and renewables misses whether a true system-wide transformation to CO₂-free energy is occurring.
Their method in Current Research in Environmental Sustainability reveals that none of the studied nations has yet achieved the full structural change required.
Source: phys.org
A Helmholtz-Zentrum Hereon study shows offshore wind farms in the North Sea are reshaping natural sediment transport, with the German Bight particularly affected.
The expansion could move up to 1.5 million tons of sediment annually, with long-term consequences for coastal ecosystems.
Source: phys.org
Researchers at Xi’an Jiaotong University improved AI models to systematically identify novel solid carbon forms, including structures thought to be harder than diamond.
The approach could unlock materials with exotic property combinations not reachable by conventional methods.
Source: phys.org
Chemists at Wageningen University & Research and Utrecht University developed an electrochemical method to produce a key chemical building block from biomass without hazardous chemicals.
The simple setup yields a precursor for plastics, pharmaceuticals, and fragrances, offering a cleaner production route.
Source: phys.org
Researchers used a spin-flip metal complex to achieve singlet fission, producing more energy carriers than photons absorbed and reaching approximately 130% efficiency.
The breakthrough could lead to significantly more powerful solar panels in the future.
Source: sciencedaily.com
Scientists created a nitrogen-tuned carbon material that captures CO₂ more efficiently and releases it at much lower temperatures, sometimes below 60 °C.
The discovery could make carbon capture cheaper by allowing the process to run on waste heat instead of high-energy input.
Source: sciencedaily.com
Planetterrian Spotlight
Supercomputer maps spliceosome motions stands out because it brings an entire molecular machine to life inside a two-million-atom simulation of the human cell. By combining computational chemistry with supercomputing power, the Italian Institute of Technology team has given researchers a dynamic view of RNA splicing that was impossible to observe directly. This level of detail could accelerate drug development for diseases caused by splicing errors, including certain cancers and genetic disorders. What to watch next is whether these simulations can be scaled to test how small molecules or mutations alter the machine’s choreography in real time.
One question: How might seeing molecular machines in motion change the way we design medicines in the next decade?
Science Deep Dive: Why appetite vanishes when you’re sick
Most people assume feeling sick simply drains your energy and that loss of appetite is just a side effect of general fatigue. In reality, specialized cells in your gut actively detect parasites and bacteria, then send targeted signals that tell the brain to suppress hunger. Right now, as you read this, those gut cells are constantly sampling what you’ve eaten and monitoring for invaders. The process builds gradually, which is why you often feel fine at first but suddenly lose interest in food once the infection takes hold. A single nerve pathway can relay these signals at speeds up to 120 metres per second, faster than most cars on the highway. This mechanism is an ancient defence that prevents you from consuming more pathogens while your immune system fights the current threat. The next time you feel that sudden disinterest in eating during an illness, remember it is not weakness but a deliberate protective response. Pay attention to how quickly appetite returns after symptoms ease; that rebound can be a useful personal signal that your body has cleared the immediate danger.
Today's findings remind us that science is steadily peeling back layers of complexity in everything from the Sun’s interior to the machines inside our own cells. Keep asking good questions.